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Concepts in bio-molecular spectroscopy: vibrational case studies on metalloenzymes
Zitatschlüssel Horch2015a
Autor Horch, M. and Hildebrandt, P. and Zebger, I.
Seiten 18222-18237
Jahr 2015
DOI 10.1039/C5CP02447A
Journal Phys. Chem. Chem. Phys.
Jahrgang 17
Verlag The Royal Society of Chemistry
Zusammenfassung Spectroscopic techniques play a major role in the elucidation of structure-function relationships of biological macromolecules. Here we describe an integrated approach for bio-molecular spectroscopy that takes into account the special characteristics of such compounds. The underlying fundamental concepts will be exemplarily illustrated by means of selected case studies on biocatalysts, namely hydrogenase and superoxide reductase. The treatise will be concluded with an overview of challenges and future prospects, laying emphasis on functional dynamics, in vivo studies, and computational spectroscopy.
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