direkt zum Inhalt springen

direkt zum Hauptnavigationsmenü

Sie sind hier

TU Berlin

Inhalt des Dokuments

Articles

Induction of photochemical auto-reduction of cytochrome-c oxidase by an organic peroxide
Zitatschlüssel ISI:000088738000011
Autor Matysik, J and Hildebrandt, P and Ludwig, B
Seiten 125-130
Jahr 2000
ISSN 0005-2728
Adresse PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
Journal Biochim. Biophys. Acta
Jahrgang 1459
Nummer 1
Monat JUL 20
Verlag ELSEVIER SCIENCE BV
Zusammenfassung Cytochrome-e oxidase aa(3) (CcO) from Paracoccus denitrificans interacts with tertiary butyl hydroperoxide (t-Bu-O-O-H, TBHP) by forming an adduct as indicated by an absorption shift at 408/432 nm and the induction of photochemical auto-reduction. The adduct was stable at room temperature for several days even under aerobic conditions. Upon irradiation (413 nm) of the adduct, a photoproduct, similar to the oxygenated mixed valence species (607 nm form), was formed, as indicated by the 418/442 and 607 nm signals in the absorption-difference spectrum. It is concluded that the adduct formation changes the photochemical properties of heme a(3). A molecular model for the binding mechanism of TBHP to CcO and for the photochemistry of heme a(3)-TBHP adduct is proposed. (C) 2000 Elsevier Science B.V. All rights reserved.
Typ der Publikation Article
Download Bibtex Eintrag

Zusatzinformationen / Extras

Direktzugang

Schnellnavigation zur Seite über Nummerneingabe

Diese Seite verwendet Matomo für anonymisierte Webanalysen. Mehr Informationen und Opt-Out-Möglichkeiten unter Datenschutz.