direkt zum Inhalt springen

direkt zum Hauptnavigationsmenü

Sie sind hier

TU Berlin

Inhalt des Dokuments

Publikationen

Resonance Raman Spectroscopy on [NiFe] Hydrogenase Provides Structural Insights into Catalytic Intermediates and Reactions
Zitatschlüssel ISI:000339228200019
Autor Horch, Marius and Schoknecht, Janna and Mroginski, Maria Andrea and Lenz, Oliver and Hildebrandt, Peter and Zebger, Ingo
Seiten 9870-9873
Jahr 2014
ISSN 0002-7863
DOI 10.1021/ja505119q
Adresse 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
Journal JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Jahrgang 136
Nummer 28
Monat JUL 16
Verlag AMER CHEMICAL SOC
Zusammenfassung [NiFe] hydrogenases catalyze the reversible cleavage of hydrogen and, thus, represent model systems for the investigation and exploitation of emission-free energy conversion processes. Valuable information on the underlying molecular mechanisms can be obtained by spectroscopic techniques that monitor individual catalytic intermediates. Here, we employed resonance Raman spectroscopy and extended it to the entire binuclear active site of an oxygen-tolerant [NiFe] hydrogenase by probing the metal-ligand modes of both the Fe and, for the first time, the Ni ion. Supported by theoretical methods, this approach allowed for monitoring H-transfer from the active site and revealed novel insights into the so far unknown structure and electronic configuration of the hydrogen-binding intermediate of the catalytic cycle, thereby providing key information about catalytic intermediates and reactions of biological hydrogen activation.
Typ der Publikation Article
Download Bibtex Eintrag

Zusatzinformationen / Extras

Direktzugang

Schnellnavigation zur Seite über Nummerneingabe

Diese Seite verwendet Matomo für anonymisierte Webanalysen. Mehr Informationen und Opt-Out-Möglichkeiten unter Datenschutz.